Publications

Preclinical evaluation of [C-11]GW457427 as a tracer for neutrophil elastase

Estrada, Sergio; Elgland, Mathias; Selvaraju, Ram Kumar; Mani, Kevin et al.

Part of Nuclear Medicine and Biology, p. 62-71, 2022.

DOI for Preclinical evaluation of [C-11]GW457427 as a tracer for neutrophil elastase Download full text (pdf) of Preclinical evaluation of [C-11]GW457427 as a tracer for neutrophil elastase

E-Cigarette Aerosol Deposition and Disposition of [C-11]Nicotine Using Positron Emission Tomography: A Comparison of Nicotine Uptake in Lungs and Brain Using Two Different Nicotine Formulations

Wall, Anders; Roslin, Sara; Borg, Beatrice; McDermott, Simon et al.

Part of Pharmaceuticals, 2022.

DOI for E-Cigarette Aerosol Deposition and Disposition of [C-11]Nicotine Using Positron Emission Tomography: A Comparison of Nicotine Uptake in Lungs and Brain Using Two Different Nicotine Formulations Download full text (pdf) of E-Cigarette Aerosol Deposition and Disposition of [C-11]Nicotine Using Positron Emission Tomography: A Comparison of Nicotine Uptake in Lungs and Brain Using Two Different Nicotine Formulations

Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study

Wechalekar, Ashutosh; Antoni, Gunnar; Al Azzam, Wasfi; Bergstrom, Mats et al.

Part of BMC Cardiovascular Disorders, 2022.

DOI for Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study Download full text (pdf) of Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study

A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media

Rokka, Johanna; Nordeman, Patrik; Bergman, Sara; Eriksson, Jonas

Part of Journal of labelled compounds & radiopharmaceuticals, p. 447-455, 2021.

DOI for A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media Download full text (pdf) of A comparative study on Suzuki‐type 11 C‐methylation of aromatic organoboranes performed in two reaction media

Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

Persson, Jonas; Puuvuori, Emmi; Zhang, Bo; Velikyan, Irina et al.

Part of Scientific Reports, 2021.

DOI for Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69 Download full text (pdf) of Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

Theranostic Approach in Breast Cancer A Treasured Tailor for Future Oncology

Jokar, Narges; Velikyan, Irina; Ahmadzadehfar, Hojjat; Rekabpour, Seyed Javad et al.

Part of Clinical Nuclear Medicine, p. E410-E420, 2021.

DOI for Theranostic Approach in Breast Cancer A Treasured Tailor for Future Oncology

News ways of understanding the complex biology of diabetes using PET

Eriksson, Olof; Långström, Bengt; Antoni, Gunnar

Part of Nuclear Medicine and Biology, p. 65-71, 2021.

DOI for News ways of understanding the complex biology of diabetes using PET

PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Cheung, Pierre; Zhang, Bo; Puuvuori, Emmi; Estrada, Sergio et al.

Part of Biomedicines, 2021.

DOI for PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs Download full text (pdf) of PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Rosestedt, Maria; Velikyan, Irina; Rosenström, Ulrika; Estrada, Sergio et al.

Part of Nuclear Medicine and Biology, p. 54-62, 2021.

DOI for Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1 Download full text (pdf) of Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Tau aggregation and increased neuroinflammation in athletes after sports-related concussions and in traumatic brain injury patients – A PET/MR study

Marklund, Niklas; Vedung, Fredrik; Lubberink, Mark; Tegner, Yelverton et al.

Part of NeuroImage, 2021.

DOI for Tau aggregation and increased neuroinflammation in athletes after sports-related concussions and in traumatic brain injury patients – A PET/MR study Download full text (pdf) of Tau aggregation and increased neuroinflammation in athletes after sports-related concussions and in traumatic brain injury patients – A PET/MR study

Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

Espes, Daniel; Carlsson, Per-Ola; Selvaraju, Ram Kumar; Rosestedt, Maria et al.

Part of Diabetes, p. 966-975, 2021.

DOI for Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

¹⁸F-Radiolabeling and Preliminary Evaluation of a HSP₉₀ ligand

Nordeman, Patrik; Jayendra, Z. P.; Briard, E.; Li, Su-Chen et al.

Part of European Journal of Pharmaceutical Sciences, 2021.

DOI for ¹⁸F-Radiolabeling and Preliminary Evaluation of a HSP₉₀ ligand

Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain

Syvänen, Stina; Fang, Xiaotian T.; Faresjö, Rebecca; Rokka, Johanna et al.

Part of ACS Chemical Neuroscience, p. 4460-4468, 2020.

DOI for Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain Download full text (pdf) of Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain

Quantification of aromatase binding in the female human brain using [¹¹ C]cetrozole positron emission tomography.

Jonasson, My; Nordeman, Patrik; Eriksson, Jonas; Wilking, Helena et al.

Part of Journal of Neuroscience Research, p. 2208-2218, 2020.

DOI for Quantification of aromatase binding in the female human brain using [¹¹ C]cetrozole positron emission tomography. Download full text (pdf) of Quantification of aromatase binding in the female human brain using [¹¹ C]cetrozole positron emission tomography.

Phosphodiesterase 10A levels are related to striatal function in schizophrenia: a combined positron emission tomography and functional magnetic resonance imaging study

Persson, Jonas; Szalisznyo, Krisztina; Antoni, Gunnar; Wall, Anders et al.

Part of European Archives of Psychiatry and Clinical Neuroscience, p. 451-459, 2020.

DOI for Phosphodiesterase 10A levels are related to striatal function in schizophrenia: a combined positron emission tomography and functional magnetic resonance imaging study Download full text (pdf) of Phosphodiesterase 10A levels are related to striatal function in schizophrenia: a combined positron emission tomography and functional magnetic resonance imaging study

Improved synthesis of SV2A targeting radiotracer [11C]UCB-J

Rokka, Johanna; Schlein, Eva; Eriksson, Jonas

Part of EJNMMI Radiopharmacy and Chemistry, 2019.

DOI for Improved synthesis of SV2A targeting radiotracer [11C]UCB-J Download full text (pdf) of Improved synthesis of SV2A targeting radiotracer [11C]UCB-J

Synaptic vesicle protein 2A as a potential biomarker in synaptopathies

Heurling, Kerstin; Ashton, Nicholas J; Leuzy, Antoine; Zimmer, Eduardo R et al.

Part of Molecular and Cellular Neuroscience, p. 34-42, 2019.

DOI for Synaptic vesicle protein 2A as a potential biomarker in synaptopathies Download full text (pdf) of Synaptic vesicle protein 2A as a potential biomarker in synaptopathies

Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim et al.

Part of Nuclear Medicine and Biology, p. 1-10, 2019.

DOI for Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass Download full text (pdf) of Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain

Fang, Xiaotian T.; Hultqvist, Greta; Meier, Silvio R.; Antoni, Gunnar et al.

Part of NeuroImage, p. 881-888, 2019.

DOI for High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain

Phase 0, Including Microdosing Approaches: Applying the Three Rs and Increasing the Efficiency of Human Drug Development

Burt, Tal; Vuong, Le Thuy; Baker, Elizabeth; Young, Graeme C. et al.

Part of ATLA (Alternatives to Laboratory Animals), p. 335-346, 2018.

The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass.

Jahan, Mahabuba; Johnström, Peter; Selvaraju, Ramkumar; Svedberg, Marie et al.

Part of EJNMMI Research, 2018.

DOI for The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass. Download full text (pdf) of The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass.

Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Mitran, Bogdan; Güler, Rezan; Roche, Francis P.; Lindström, Elin et al.

Part of Theranostics, p. 4462-4476, 2018.

DOI for Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model Download full text (pdf) of Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease

Olsen, Malin; Aguilar, Ximena; Sehlin, Dag; Fang, Xiaotian T. et al.

Part of Molecular Imaging and Biology, p. 605-614, 2018.

DOI for Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease Download full text (pdf) of Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease

Non-invasive tri-modal visualisation via PET/SPECT/μCT of recombinant human bone morphogenetic protein-2 retention and associated bone regeneration: A proof of concept

Hulsart Billström, Gry; Selvaraju, Ramkumar; Estrada, Sergio; Lubberink, Mark et al.

Part of Journal of Controlled Release, p. 178-186, 2018.

DOI for Non-invasive tri-modal visualisation via PET/SPECT/μCT of recombinant human bone morphogenetic protein-2 retention and associated bone regeneration: A proof of concept Download full text (pdf) of Non-invasive tri-modal visualisation via PET/SPECT/μCT of recombinant human bone morphogenetic protein-2 retention and associated bone regeneration: A proof of concept

In Vivo Visualization of beta-Cells by Targeting of GPR44

Eriksson, Olof; Johnström, Peter; Cselenyi, Zsolt; Jahan, Mahabuba et al.

Part of Diabetes, p. 182-192, 2018.

DOI for In Vivo Visualization of beta-Cells by Targeting of GPR44

Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4

Eriksson, Olof; Rosenström, Ulrika; Selvaraju, Ram Kumar; Eriksson, Barbro et al.

Part of Acta Diabetologica, p. 1039-1045, 2017.

DOI for Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4 Download full text (pdf) of Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4

Palladium-mediated C-11-carbonylations using aryl halides and cyanamide

Nordeman, Patrik; Chow, Shiao Y.; Odell, A. F.; Antoni, Gunnar et al.

Part of Organic and biomolecular chemistry, p. 4875-4881, 2017.

DOI for Palladium-mediated C-11-carbonylations using aryl halides and cyanamide

Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [(11)C]ABP688 PET imaging and ex vivo immunoblotting

Fang, Xiaotian T.; Eriksson, Jonas; Antoni, Gunnar; Yngve, Ulrika et al.

Part of Neuropharmacology, p. 293-300, 2017.

DOI for Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [(11)C]ABP688 PET imaging and ex vivo immunoblotting

Blood Flow Quantitation by Positron Emission Tomography During Selective Antegrade Cerebral Perfusion

Tovedal, Thomas; Lubberink, Mark; Morell, Arvid; Estrada, Sergio et al.

Part of Annals of Thoracic Surgery, p. 610-616, 2017.

DOI for Blood Flow Quantitation by Positron Emission Tomography During Selective Antegrade Cerebral Perfusion

Ga-68/PET imaging and quantification of fibrosis using peptide-based tracers

Velikyan, Irina; Rosenström, Ulrika; Eriksson, Olof; Antoni, Gunnar

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S73-S73, 2016.

[C-11]UCB-A, a novel PET tracer for synaptic vesicle protein 2 A

Estrada, Sergio; Lubberink, Mark; Thibblin, Alf; Sprycha, Margareta et al.

Part of Nuclear Medicine and Biology, p. 325-332, 2016.

DOI for [C-11]UCB-A, a novel PET tracer for synaptic vesicle protein 2 A

C-11 and F-18 Radiolabeling of Tetra- and Pentathiophenes as PET-Ligands for Amyloid Protein Aggregates

Nordeman, Patrik; Johansson, Leif B. G.; Back, Marcus; Estrada, Sergio et al.

Part of ACS Medicinal Chemistry Letters, p. 368-373, 2016.

DOI for C-11 and F-18 Radiolabeling of Tetra- and Pentathiophenes as PET-Ligands for Amyloid Protein Aggregates

Tracer kinetic analysis of (S)-18F-THK5117 as a PET tracer for assessing tau pathology.

Jonasson, My; Wall, Anders; Chiotis, Konstantinos; Saint-Aubert, Laure et al.

Part of Journal of Nuclear Medicine, p. 574-581, 2016.

DOI for Tracer kinetic analysis of (S)-18F-THK5117 as a PET tracer for assessing tau pathology.

Feasibility of affibody-based bioorthogonal chemistry-mediated radionuclide pretargeting

Altai, Mohamed; Perols, Anna; Tsourma, Maria; Mitran, Bogdan et al.

Part of Journal of Nuclear Medicine, p. 431-436, 2016.

DOI for Feasibility of affibody-based bioorthogonal chemistry-mediated radionuclide pretargeting

Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors

Honarvar, Hadis; Westerlund, Kristina; Altai, Mohamed; Sandström, Mattias et al.

Part of Theranostics, p. 93-103, 2016.

DOI for Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors Download full text (pdf) of Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors

Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model.

Spiegelberg, Diana; Mortensen, Anja C; Selvaraju, Ram K; Eriksson, Olof et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 974-982, 2016.

DOI for Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model. Download full text (pdf) of Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model.

Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma

Haylock, Anna-Karin; Spiegelberg, Diana; Mortensen, Anja C.; Selvaraju, Ram K. et al.

Part of International journal of oncology, p. 461-470, 2016.

DOI for Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma Download full text (pdf) of Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma

Comparing the measured affinity of 111In-labeled ligands for cellular receptors by monitoring gamma, beta, or x-ray radiation with three different LigandTracer® devices

Orlova, Anna; varasteh, Zohreh

Part of Journal of Radioanalytical and Nuclear Chemistry, p. 823-828, 2015.

Affibody-mediated PET imaging of HER3 expression in malignant tumours

Rosestedt, Maria; Andersson, Ken G.; Mitran, Bogdan; Tolmachev, Vladimir et al.

Part of Scientific Reports, 2015.

DOI for Affibody-mediated PET imaging of HER3 expression in malignant tumours Download full text (pdf) of Affibody-mediated PET imaging of HER3 expression in malignant tumours

Systematic screening of imaging biomarkers for the Islets of Langerhans, among clinically available positron emission tomography tracers

Karlsson, Filip; Antonodimitrakis, Pantelis Clewemar; Eriksson, Olof

Part of Nuclear Medicine and Biology, p. 762-769, 2015.

DOI for Systematic screening of imaging biomarkers for the Islets of Langerhans, among clinically available positron emission tomography tracers

Synthesis of enantiopure angiotensin II type 2 receptor [AT(2)R] antagonist EMA401

Wakchaure, Prasad B.; Bremberg, Ulf; Wannberg, Johan; Larhed, Mats

Part of Tetrahedron, p. 6881-6887, 2015.

DOI for Synthesis of enantiopure angiotensin II type 2 receptor [AT(2)R] antagonist EMA401

ADAPT, a novel scaffold protein-based probe for radionuclide imaging of molecular targets that are expressed in disseminated cancers

Garousi, Javad; Lindbo, Sarah; Nilvebrant, Johan; Åstrand, Mikael et al.

Part of Cancer Research, p. 4364-4371, 2015.

DOI for ADAPT, a novel scaffold protein-based probe for radionuclide imaging of molecular targets that are expressed in disseminated cancers

Comparative evaluation of 111In-labeled NOTA‑conjugated affibody molecules for visualization of HER3 expression in malignant tumors

Andersson, Ken G.; Rosestedt, Maria; Varasteh, Zohreh; Malm, Magdalena et al.

Part of Oncology Reports, p. 1042-1048, 2015.

DOI for Comparative evaluation of 111In-labeled NOTA‑conjugated affibody molecules for visualization of HER3 expression in malignant tumors Download full text (pdf) of Comparative evaluation of 111In-labeled NOTA‑conjugated affibody molecules for visualization of HER3 expression in malignant tumors

Visualization of regional tau deposits using (3)H-THK5117 in Alzheimer brain tissue

Lemoine, Laetitia; Saint-Aubert, Laure; Marutle, Amelia; Antoni, Gunnar et al.

Part of Acta neuropathologica communications, 2015.

DOI for Visualization of regional tau deposits using (3)H-THK5117 in Alzheimer brain tissue Download full text (pdf) of Visualization of regional tau deposits using (3)H-THK5117 in Alzheimer brain tissue

Quantification of [18F]DPA-714 binding in the human brain: initial studies in healthy controls and Alzheimer's disease patients

Golla, Sandeep S V; Boellaard, Ronald; Oikonen, Vesa; Hoffmann, Anja et al.

Part of Journal of Cerebral Blood Flow and Metabolism, p. 766-772, 2015.

DOI for Quantification of [18F]DPA-714 binding in the human brain: initial studies in healthy controls and Alzheimer's disease patients

Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity

Strand, Joanna; Nordeman, Patrik; Honarvar, Hadis; Altai, Mohamed et al.

Part of ChemistryOpen, p. 174-182, 2015.

DOI for Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity Download full text (pdf) of Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity

Continued rapid growth in Ga-68 applications: update 2013 to June 2014

Velikyan, Irina

Part of Journal of labelled compounds & radiopharmaceuticals, p. 99-121, 2015.

DOI for Continued rapid growth in Ga-68 applications: update 2013 to June 2014

Synthesis and biological evaluation of [C-11]AZ12504948; a novel tracer for imaging of glucokinase in pancreas and liver

Jahan, M.; Johnstrom, P.; Nag, S.; Takano, A. et al.

Part of Nuclear Medicine and Biology, p. 387-394, 2015.

DOI for Synthesis and biological evaluation of [C-11]AZ12504948; a novel tracer for imaging of glucokinase in pancreas and liver

Comparing the measured affinity of (111) In-labeled ligands for cellular receptors by monitoring gamma, beta, or X-ray radiation with three different LigandTracer (R) devices

Varasteh, Zohreh; Orlova, Anna

Part of Journal of Radioanalytical and Nuclear Chemistry, p. 823-828, 2015.

DOI for Comparing the measured affinity of (111) In-labeled ligands for cellular receptors by monitoring gamma, beta, or X-ray radiation with three different LigandTracer (R) devices

Development of carbon-11 labelled PET tracers-radiochemical and technological challenges in a historic perspective

Antoni, Gunnar

Part of Journal of labelled compounds & radiopharmaceuticals, p. 65-72, 2015.

DOI for Development of carbon-11 labelled PET tracers-radiochemical and technological challenges in a historic perspective