ENABLE - European Gram Negative AntiBacterial Engine
Antimicrobial resistance is a major public health threat. Despite the strong need for new antimicrobials, very few new, effective antibiotics have been brought to the market in the last decades. The ENABLE project within IMI’s New Drugs for Bad Bugs (ND4BB) programme, is working to advance the development of potential antibiotics against Gram-negative bacteria, such as Escherichia coli. The ultimate goal is to progress at least one compound into Phase 1 clinical trials.
As part of the ENABLE consortium our department contributes with overall project management, medicinal chemistry, computer-aided drug design, IT system management and Hit-to-Lead (H2L) programme co-leadership