Publication list

Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences

Velikyan, Irina; Bossart, Martin; Haack, Torsten; Laitinen, Iina et al.

Part of Pharmaceuticals, 2023.

DOI for Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences Download full text (pdf) of Imaging of the Glucose-Dependent Insulinotropic Polypeptide Receptor Using a Novel Radiolabeled Peptide Rationally Designed Based on Endogenous GIP and Synthetic Exendin-4 Sequences

[¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44

Cheung, Pierre; Amin, Mohammad A.; Zhang, Bo; Lechi, Francesco et al.

Part of Pharmaceutics, 2023.

DOI for [¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44 Download full text (pdf) of [¹⁸F]MK-7246 for Positron Emission Tomography Imaging of the Beta-Cell Surface Marker GPR44

PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

Puuvuori, Emmi; Chiodaroli, Elena; Estrada, Sergio; Cheung, Pierre et al.

Part of Journal of Nuclear Medicine, p. 423-429, 2023.

DOI for PET imaging of neutrophil elastase with ¹¹C-GW457427 in Acute Respiratory Distress Syndrome in pigs

Monitoring beta-Cell Survival After Intrahepatic Islet Transplantation Using Dynamic Exendin PET Imaging: A Proof-of-Concept Study in Individuals With Type 1 Diabetes

Jansen, Theodorus J. P.; Buitinga, Mijke; Boss, Marti; Nijhoff, Michiel F. et al.

Part of Diabetes, p. 898-907, 2023.

DOI for Monitoring beta-Cell Survival After Intrahepatic Islet Transplantation Using Dynamic Exendin PET Imaging: A Proof-of-Concept Study in Individuals With Type 1 Diabetes

Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β

Wegrzyniak, Olivia; Zhang, Bo; Rokka, Johanna; Rosestedt, Maria et al.

Part of EJNMMI Radiopharmacy and Chemistry, 2023.

DOI for Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β Download full text (pdf) of Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β

In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with ¹¹C-NES

Antoni, Gunnar; Lubberink, Mark; Sörensen, Jens; Lindström, Elin et al.

Part of Journal of Nuclear Medicine, p. 145-148, 2023.

DOI for In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with ¹¹C-NES Download full text (pdf) of In Vivo Visualization and Quantification of Neutrophil Elastase in Lungs of COVID-19 Patients: A First-in-Humans PET Study with ¹¹C-NES

Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

Bossart, Martin; Wagner, Michael; Elvert, Ralf; Evers, Andreas et al.

Part of Cell Metabolism, p. 59-+, 2022.

DOI for Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

Glucagonlike Peptide-1 Receptor Imaging in Individuals with Type 2 Diabetes

Eriksson, Olof; Velikyan, Irina; Haack, Torsten; Bossart, Martin et al.

Part of Journal of Nuclear Medicine, p. 794-800, 2022.

DOI for Glucagonlike Peptide-1 Receptor Imaging in Individuals with Type 2 Diabetes

Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model

Samanta, Sumanta; Le Joncour, Vadim; Wegrzyniak, Olivia; Rangasami, Vignesh K. et al.

Part of Advanced Therapeutics, 2022.

DOI for Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model Download full text (pdf) of Heparin-Derived Theranostic Nanoprobes Overcome the Blood-Brain Barrier and Target Glioma in Murine Model

PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE

Puuvuori, Emmi; Liggieri, Francesco; Velikyan, Irina; Chiodaroli, Elena et al.

Part of EJNMMI Research, 2022.

DOI for PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE Download full text (pdf) of PET-CT imaging of pulmonary inflammation using [Ga-68]Ga-DOTA-TATE

Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Rosestedt, Maria; Velikyan, Irina; Rosenström, Ulrika; Estrada, Sergio et al.

Part of Nuclear Medicine and Biology, p. 54-62, 2021.

DOI for Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1 Download full text (pdf) of Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Drug Occupancy Assessment at the Glucose-Dependent Insulinotropic Polypeptide Receptor by Positron Emission Tomography

Eriksson, Olof; Velikyan, Irina; Haack, Torsten; Bossart, Martin et al.

Part of Diabetes, p. 842-853, 2021.

DOI for Drug Occupancy Assessment at the Glucose-Dependent Insulinotropic Polypeptide Receptor by Positron Emission Tomography

Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

Espes, Daniel; Carlsson, Per-Ola; Selvaraju, Ram Kumar; Rosestedt, Maria et al.

Part of Diabetes, p. 966-975, 2021.

DOI for Longitudinal Assessment of ¹¹C-5-Hydroxytryptophan Uptake in Pancreas After Debut of Type 1 Diabetes

Imaging of the Glucagon Receptor in Subjects with Type 2 Diabetes

Eriksson, Olof; Velikyan, Irina; Haack, Torsten; Bossart, Martin et al.

Part of Journal of Nuclear Medicine, p. 833-838, 2021.

DOI for Imaging of the Glucagon Receptor in Subjects with Type 2 Diabetes

News ways of understanding the complex biology of diabetes using PET

Eriksson, Olof; Långström, Bengt; Antoni, Gunnar

Part of Nuclear Medicine and Biology, p. 65-71, 2021.

DOI for News ways of understanding the complex biology of diabetes using PET

Recent Progress in the Molecular Imaging of Nonalcoholic Fatty Liver Disease

Wegrzyniak, Olivia; Rosestedt, Maria; Eriksson, Olof

Part of International Journal of Molecular Sciences, 2021.

DOI for Recent Progress in the Molecular Imaging of Nonalcoholic Fatty Liver Disease Download full text (pdf) of Recent Progress in the Molecular Imaging of Nonalcoholic Fatty Liver Disease

Improved Radiolytic Stability of a ⁶⁸Ga-labelled Collagelin Analogue for the Imaging of Fibrosis

Velikyan, Irina; Rosenström, Ulrika; Rosestedt, Maria; Eriksson, Olof et al.

Part of Pharmaceuticals, 2021.

DOI for Improved Radiolytic Stability of a ⁶⁸Ga-labelled Collagelin Analogue for the Imaging of Fibrosis Download full text (pdf) of Improved Radiolytic Stability of a ⁶⁸Ga-labelled Collagelin Analogue for the Imaging of Fibrosis

Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography

Manell, Elin; Puuvuori, Emmi; Svensson, Anna; Velikyan, Irina et al.

Part of BMJ Open Diabetes Research & Care, 2021.

DOI for Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography Download full text (pdf) of Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography

The Current State of Beta-Cell-Mass PET Imaging for Diabetes Research and Therapies

Cheung, Pierre; Eriksson, Olof

Part of Biomedicines, 2021.

DOI for The Current State of Beta-Cell-Mass PET Imaging for Diabetes Research and Therapies Download full text (pdf) of The Current State of Beta-Cell-Mass PET Imaging for Diabetes Research and Therapies

Potential of [C-11]UCB-J as a PET tracer for islets of Langerhans

Puuvuori, Emmi; Rokka, Johanna; Carlsson, Per-Ola; Li, Zhanchun et al.

Part of Scientific Reports, 2021.

DOI for Potential of [C-11]UCB-J as a PET tracer for islets of Langerhans Download full text (pdf) of Potential of [C-11]UCB-J as a PET tracer for islets of Langerhans

Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

Persson, Jonas; Puuvuori, Emmi; Zhang, Bo; Velikyan, Irina et al.

Part of Scientific Reports, 2021.

DOI for Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69 Download full text (pdf) of Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Cheung, Pierre; Zhang, Bo; Puuvuori, Emmi; Estrada, Sergio et al.

Part of Biomedicines, 2021.

DOI for PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs Download full text (pdf) of PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Advances in GLP-1 receptor targeting radiolabeled agent development and prospective of theranostics

Velikyan, Irina; Eriksson, Olof

Part of Theranostics, p. 437-461, 2020.

DOI for Advances in GLP-1 receptor targeting radiolabeled agent development and prospective of theranostics Download full text (pdf) of Advances in GLP-1 receptor targeting radiolabeled agent development and prospective of theranostics

[¹¹C]5-Hydroxy-tryptophan model for quantitative assessment of in vivo serotonin biosynthesis, retention and degradation in the endocrine pancreas

Lubberink, Mark; Eriksson, Olof

Part of American Journal of Nuclear Medicine and Molecular Imaging, p. 226-234, 2020.

Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes

Eriksson, Olof; Haack, Torsten; Hijazi, Youssef; Teichert, Lenore et al.

Part of Scientific Reports, 2020.

DOI for Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes Download full text (pdf) of Receptor occupancy of dual glucagon-like peptide 1/glucagon receptor agonist SAR425899 in individuals with type 2 diabetes

Heterogeneity of Metabolic Defects in Type 2 Diabetes and Its Relation to Reactive Oxygen Species and Alterations in Beta-Cell Mass

Elksnis, Andris; Martinell, Mats; Eriksson, Olof; Espes, Daniel

Part of Frontiers in Physiology, 2019.

DOI for Heterogeneity of Metabolic Defects in Type 2 Diabetes and Its Relation to Reactive Oxygen Species and Alterations in Beta-Cell Mass Download full text (pdf) of Heterogeneity of Metabolic Defects in Type 2 Diabetes and Its Relation to Reactive Oxygen Species and Alterations in Beta-Cell Mass

GPR44 as a Target for Imaging Pancreatic Beta-Cell Mass

Eriksson, Olof

Part of Current Diabetes Reports, 2019.

DOI for GPR44 as a Target for Imaging Pancreatic Beta-Cell Mass Download full text (pdf) of GPR44 as a Target for Imaging Pancreatic Beta-Cell Mass

Tools for Bioimaging Pancreatic beta Cells in Diabetes

Kang, Nam-Young; Soetedjo, Andreas Alvin Purnomo; Amirruddin, Nur Shabrina; Chang, Young-Tae et al.

Part of Trends in Molecular Medicine, p. 708-722, 2019.

DOI for Tools for Bioimaging Pancreatic beta Cells in Diabetes

Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI

Espes, Daniel; Manell, Elin; Rydén, Anneli; Carlbom, Lina et al.

Part of Acta Diabetologica, p. 1113-1120, 2019.

DOI for Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI Download full text (pdf) of Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI

Overeating saturated fat promotes fatty liver and ceramides compared to polyunsaturated fat: a randomized trial

Rosqvist, Fredrik; Kullberg, Joel; Ståhlman, Marcus; Cedernaes, Jonathan et al.

Part of Journal of Clinical Endocrinology and Metabolism, p. 6207-6219, 2019.

DOI for Overeating saturated fat promotes fatty liver and ceramides compared to polyunsaturated fat: a randomized trial Download full text (pdf) of Overeating saturated fat promotes fatty liver and ceramides compared to polyunsaturated fat: a randomized trial

Metabolically Active Brown Adipose Tissue Is Found in Adult Subjects with Type 1 Diabetes.

Eriksson, Olof; Selvaraju, Ramkumar; Berglund, Marie; Espes, Daniel

Part of International Journal of Molecular Sciences, 2019.

DOI for Metabolically Active Brown Adipose Tissue Is Found in Adult Subjects with Type 1 Diabetes. Download full text (pdf) of Metabolically Active Brown Adipose Tissue Is Found in Adult Subjects with Type 1 Diabetes.

Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

Eriksson, Jonas; Roy, Tamal; Sawadjoon, Supaporn; Bachmann, Kim et al.

Part of Nuclear Medicine and Biology, p. 1-10, 2019.

DOI for Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass Download full text (pdf) of Synthesis and preclinical evaluation of the CRTH2 antagonist [¹¹C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

First-in-class positron emission tomography tracer for the glucagon receptor

Velikyan, Irina; Haack, Torsten; Bossart, Martin; Evers, Andreas et al.

Part of EJNMMI Research, 2019.

DOI for First-in-class positron emission tomography tracer for the glucagon receptor Download full text (pdf) of First-in-class positron emission tomography tracer for the glucagon receptor

Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates

Eriksson, Olof; Velikyan, Irina; Haack, Torsten; Bossart, Martin et al.

Part of Scientific Reports, 2019.

DOI for Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates Download full text (pdf) of Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates

In Vivo Visualization of beta-Cells by Targeting of GPR44

Eriksson, Olof; Johnström, Peter; Cselenyi, Zsolt; Jahan, Mahabuba et al.

Part of Diabetes, p. 182-192, 2018.

DOI for In Vivo Visualization of beta-Cells by Targeting of GPR44

Cannabinoid Type 1 Receptors Are Upregulated During Acute Activation of Brown Adipose Tissue

Lahesmaa, Minna; Eriksson, Olof; Gnad, Thorsten; Oikonen, Vesa et al.

Part of Diabetes, p. 1226-1236, 2018.

DOI for Cannabinoid Type 1 Receptors Are Upregulated During Acute Activation of Brown Adipose Tissue

Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer

Gotthardt, Martin; Eizirik, Decio L.; Aanstoot, Henk-Jan; Korsgren, Olle et al.

Part of Diabetologia, p. 2516-2519, 2018.

DOI for Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer

Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4

Eriksson, Olof; Korsgren, Olle; Selvaraju, Ram Kumar; Mollaret, Marjorie et al.

Part of Acta Diabetologica, p. 49-57, 2018.

DOI for Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4 Download full text (pdf) of Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4

Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus

Carlsson, Per-Ola; Espes, Daniel; Sedigh, Amir; Rotem, Avi et al.

Part of American Journal of Transplantation, p. 1735-1744, 2018.

DOI for Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus Download full text (pdf) of Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus

The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass.

Jahan, Mahabuba; Johnström, Peter; Selvaraju, Ramkumar; Svedberg, Marie et al.

Part of EJNMMI Research, 2018.

DOI for The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass. Download full text (pdf) of The development of a GPR44 targeting radioligand [¹¹C]AZ12204657 for in vivo assessment of beta cell mass.

Increased Expression of GLP-1R in Proliferating Islets of Men1 Mice is Detectable by [Ga-68]Ga-DO3A-VS-Cys(40)- Exendin-4/PET

Monazzam, Azita; Lau, Joey; Velikyan, Irina; Li, Su-Chen et al.

Part of Scientific Reports, 2018.

DOI for Increased Expression of GLP-1R in Proliferating Islets of Men1 Mice is Detectable by [Ga-68]Ga-DO3A-VS-Cys(40)- Exendin-4/PET Download full text (pdf) of Increased Expression of GLP-1R in Proliferating Islets of Men1 Mice is Detectable by [Ga-68]Ga-DO3A-VS-Cys(40)- Exendin-4/PET

Toward molecular imaging of the free fatty acid receptor 1

Hellström-Lindahl, Ewa; Åberg, Ola; Ericsson, Cecilia; O'Mahony, Gavin et al.

Part of Acta Diabetologica, p. 663-668, 2017.

DOI for Toward molecular imaging of the free fatty acid receptor 1 Download full text (pdf) of Toward molecular imaging of the free fatty acid receptor 1

Fully automated GMP production of [Ga-68]Ga-DO3A-VS-Cys(40)-Exendin-4 for clinical use

Velikyan, Irina; Rosenström, Ulrika; Eriksson, Olof

Part of American Journal of Nuclear Medicine and Molecular Imaging, p. 111-125, 2017.

Download full text (pdf) of Fully automated GMP production of [Ga-68]Ga-DO3A-VS-Cys(40)-Exendin-4 for clinical use

[(11)C]5-Hydroxy-Tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes

Carlbom, Lina; Espes, Daniel; Lubberink, Mark; Martinell, Mats et al.

Part of Diabetes, p. 1286-1292, 2017.

DOI for [(11)C]5-Hydroxy-Tryptophan PET for Assessment of Islet Mass During Progression of Type 2 Diabetes

Metformin treatment significantly enhances intestinal glucose uptake in patients with type 2 diabetes: Results from a randomized clinical trial

Koffert, Jukka P.; Mikkola, Kirsi; Virtanen, Kirsi A.; Andersson, Anna-Maria D. et al.

Part of Diabetes Research and Clinical Practice, p. 208-216, 2017.

DOI for Metformin treatment significantly enhances intestinal glucose uptake in patients with type 2 diabetes: Results from a randomized clinical trial Download full text (pdf) of Metformin treatment significantly enhances intestinal glucose uptake in patients with type 2 diabetes: Results from a randomized clinical trial

Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4

Eriksson, Olof; Rosenström, Ulrika; Selvaraju, Ram Kumar; Eriksson, Barbro et al.

Part of Acta Diabetologica, p. 1039-1045, 2017.

DOI for Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4 Download full text (pdf) of Species differences in pancreatic binding of DO3A-VS-Cys40-Exendin4

Combined PET and microdialysis for in vivo estimation of drug blood-brain barrier transport and brain unbound concentrations

Gustafsson, Sofia; Eriksson, Jonas; Syvänen, Stina; Eriksson, Olof et al.

Part of NeuroImage, p. 177-186, 2017.

DOI for Combined PET and microdialysis for in vivo estimation of drug blood-brain barrier transport and brain unbound concentrations

Radiochemistry and Preclinical Evaluation of Two Novel Peptide Analogues Targeting Glucagon Receptor for AntiDiabetic Drug Development

Velikyan, Irina; Bossart, M.; Haack, T.; Laitinen, I. et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S159-S160, 2017.

Cannabinoid CB1 receptors in human brown adipose tissue during cold exposure

Lahesmaa, M.; Eriksson, Olof; Oikonen, V.; Bucci, M. et al.

Part of Diabetologia, p. S50-S50, 2016.

Ga-68/PET imaging and quantification of fibrosis using peptide-based tracers

Velikyan, Irina; Rosenström, Ulrika; Eriksson, Olof; Antoni, Gunnar

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S73-S73, 2016.