Publications
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Transforming Cross-Linked Cyclic Dimers of KR-12 into Stable and Potent Antimicrobial Drug Leads.
(2023). Biomedicines, . vol. 11 DOI -
A stable cyclized antimicrobial peptide derived from LL-37 with host immunomodulatory effects and activity against uropathogens.
(2022). Cellular and Molecular Life Sciences (CMLS), . vol. 79 DOI -
The Influence of Plant Stress Hormones and Biotic Elicitors on Cyclotide Production in Viola uliginosa Cell Suspension Cultures.
(2022). PLANTS, . vol. 11 DOI -
Spatial Distribution and Stability of Cholinesterase Inhibitory Protoberberine Alkaloids from Papaver setiferum.
(2022). Journal of Natural Products, . vol. 85, ss. 215-224 DOI -
Solution NMR and racemic crystallography provide insights into a novel structural class of cyclic plant peptides.
(2021). RSC CHEMICAL BIOLOGY, . vol. 2, ss. 1682-1691 DOI -
The involvement of cyclotides in mutual interactions of violets and the two-spotted spider mite.
(2022). Scientific Reports, . vol. 12 DOI -
Barrettides: A Peptide Family Specifically Produced by the Deep-Sea Sponge Geodia barretti.
(2021). Journal of Natural Products, vol. 84, ss. 3138-3146 DOI -
Cyclotide host-defense tailored for species and environments in violets from the Canary Islands.
(2021). Scientific Reports, . vol. 11 DOI -
Antimicrobial and antioxidant activity of Evernia prunastri extracts and their isolates.
(2021). World Journal of Microbiology & Biotechnology, . vol. 37 DOI -
Antioxidant properties and phenolic profiling by UPLC-QTOF-MS of Ajwah, Safawy and Sukkari cultivars of date palm.
(2021). Biochemistry and Biophysics Reports, . vol. 25 DOI -
Tropical vibes from Sri Lanka - cyclotides from Viola betonicifolia by transcriptome and mass spectrometry analysis.
(2021). Phytochemistry, . vol. 187 DOI -
Editorial: Natural Antimicrobial Peptides: Hope for New Antibiotic Lead Molecules.
(2021). Frontiers in Pharmacology, vol. 12 DOI -
The life cycle of cyclotides: biosynthesis and turnover in plant cells.
(2020). Plant Cell Reports, . vol. 39, ss. 1359-1367 DOI -
Sulfadiazine Masquerading as a Natural Product from Scilla madeirensis (Scilloideae).
(2020). Journal of Natural Products, . vol. 83, ss. 1305-1308 DOI -
Screening for bioactive secondary metabolites in Sri Lankan medicinal plants by microfractionation and targeted isolation of antimicrobial flavonoids from Derris scandens.
(2020). Journal of Ethnopharmacology, . vol. 246 DOI -
Exploring the limits of cyanobactin macrocyclase PatGmac: Cyclisation of PawS derived peptide sunflower trypsin inhibitor-1 and cyclotide kalata B1.
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Backbone Cyclization and Dimerization of LL-37-Derived Peptides Enhance Antimicrobial Activity and Proteolytic Stability.
(2020). Frontiers in Microbiology DOI -
Functional characterization of the nemertide alpha family of peptide toxins.
(2021). Journal of Natural Products, . vol. 84, ss. 2121-2128 DOI -
Repertoire Studies in Rheumatoid Arthritis Reveal B-Cell Distortions and Baseline Shifts in Unmutated IgG.
(2018). Arthritis & Rheumatology, . vol. 70 -
How Does the Sweet Violet (Viola odorata L.) Fight Pathogens and Pests - Cyclotides as a Comprehensive Plant Host Defense System.
(2018). Frontiers in Plant Science, . vol. 9 DOI -
Stabilized Cyclic Peptides as Scavengers of Autoantibodies: Neutralization of Anticitrullinated Protein/Peptide Antibodies in Rheumatoid Arthritis.
(2018). ACS Chemical Biology, . vol. 13, ss. 1525-1535 DOI -
Alanine and Lysine Scans of the LL-37-Derived Peptide Fragment KR-12 Reveal Key Residues for Antimicrobial Activity.
(2018). ChemBioChem (Print), . vol. 19, ss. 931-939 DOI -
Peptide ion channel toxins from the bootlace worm, the longest animal on Earth.
(2018). Scientific Reports, . vol. 8 DOI -
The toxicity of ribbon worms: Alpha-nemertides or tetrodotoxin, or both?.
(2016). Planta Medica, vol. 82 DOI -
Synthesis of cyclic citrullinated peptides targeting rheumatoid arthritis autoantibodies based on sunflower trypsin inhibitors.
(2016). Planta Medica, vol. 82 DOI -
Fungi as a source for antibacterial compounds.
(2016). Planta Medica, vol. 82 DOI -
Circular disulfide-rich peptide scaffolds as anti-citrullinated peptide antibody inhibitors.
(2016). Planta Medica, vol. 82 DOI -
Peptide biodiscovery from plants and animals: structure to function.
(2016). Planta Medica, vol. 82 DOI -
Peptide toxins from the longest animal on earth.
(2016). Planta Medica, vol. 82 DOI -
Engineering of KR-12: A minimalized domain derived from human host defense peptide LL-37 into a potent antimicrobial drug lead.
(2016). Planta Medica, . vol. 82 DOI -
35 Years of Marine Natural Product Research in Sweden: Cool Molecules and Models from Cold Waters..
(2017). Progress in molecular and subcellular biology, vol. 55, ss. 1-34 DOI -
Cyclotide Evolution: Insights from the Analyses of Their Precursor Sequences, Structures and Distribution in Violets (Viola).
(2017). Frontiers in Plant Science, vol. 8 DOI -
Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins.
(2017). Frontiers in Chemistry, . vol. 5 DOI -
Bactericidal activity of cyclotides where phosphatidylethanolamine-lipid selectivity determines antimicrobial spectra.
(2017). Biochimica et Biophysica Acta - Biomembranes, . vol. 1859, ss. 1986-2000 DOI -
Single-step purification of cyclotides using affinity chromatography.
(2017). Biopolymers, vol. 108 DOI -
Resistance to the Cyclotide Cycloviolacin O2 in Salmonella enterica Caused by Different Mutations That Often Confer Cross-Resistance or Collateral Sensitivity to Other Antimicrobial Peptides.
(2017). Antimicrobial Agents and Chemotherapy, vol. 61 DOI -
Engineering Of A Minimalized Domain Derived From Human Host Defense Peptide LL-37 Into A Stable And Potent Antimicrobial Drug Lead.
(2016). Journal of Peptide Science, vol. 22, ss. S184-S186 DOI -
Bacterial Resistance To A Cyclic Antimicrobial Peptide.
(2016). Journal of Peptide Science, vol. 22, ss. S180-S180 DOI -
Anti-Citrullinated Peptide Antibody Inhibitors Based On Sunflower Trypsin Inhibitor-1 Scaffold For Potential Anti-Rheumatoid Arthritis Activity.
(2016). Journal of Peptide Science, vol. 22, ss. S170-S170 DOI -
Improved method for quantitative analysis of the cyclotide kalata B1 in plasma and brain homogenate.
(2016). Biopolymers, vol. 106, ss. 910-916 DOI -
Nomenclature of homodetic cyclic peptides produced from ribosomal precursors: An IUPAC task group interim report.
(2016). Biopolymers, vol. 106, ss. 917-924 DOI -
The "PepSAVI-MS" Pipeline for Natural Product Bioactive Peptide Discovery.
(2017). Analytical Chemistry, vol. 89, ss. 1194-1201 DOI -
Immunolocalization of cyclotides in plant cells, tissues and organ supports their role in host defense.
(2016). Planta, vol. 244, ss. 1029-1040 DOI -
Selective membrane disruption by the cyclotide kalata B7: complex ions and essential functional groups in the phosphatidylethanolamine binding pocket.
(2016). Biochimica et Biophysica Acta, vol. 1858, ss. 1317-1327 DOI -
Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis..
(2016). Proceedings of the National Academy of Sciences of the United States of America, vol. 113, ss. 3960-3965 DOI -
The Bacterial (Vibrio alginolyticus) Production of Tetrodotoxin in the Ribbon Worm Lineus longissimus-Just a False Positive?.
(2016). Marine Drugs, vol. 14 DOI -
Cyclotides in the Violaceae.
(2015). I Craik, David J. (red.) Plant Cyclotides, . ss. 15-49 DOI -
Synthesis, Structural Characterization, and Bioactivity of the Stable Peptide RCB-1 from Ricinus communis.
(2015). Journal of natural products (Print), vol. 78, ss. 2545-2551 DOI -
Distribution of circular proteins in plants: large-scale mapping of cyclotides in the Violaceae.
(2015). Frontiers in Plant Science, vol. 6 DOI -
Exogenous plant hormones and cyclotide expression in Viola uliginosa (Violaceae).
(2015). Phytochemistry, vol. 117, ss. 527-536 DOI -
Isolation, Characterization, and Synthesis of the Barrettides: Disulfide-Containing Peptides from the Marine Sponge Geodia barretti.
(2015). Journal of natural products (Print), vol. 78, ss. 1886-1893 DOI -
Targeting of anti-citrullinated protein/peptide antibodies in rheumatoid arthritis using peptides mimicking endogenously citrullinated fibrinogen antigens.
(2015). Arthritis Research & Therapy, vol. 17 DOI -
A Cactus-Derived Toxin-Like Cystine Knot Peptide with Selective Antimicrobial Activity.
(2015). ChemBioChem (Print), vol. 16, ss. 1068-1077 DOI -
Affinity states of biocides determine bioavailability and release rates in marine paints.
(2015). Biofouling (Print), vol. 31, ss. 201-210 DOI -
Poisoning with Cicuta virosa in Sweden.
(2015). Clinical Toxicology, vol. 53, ss. 345-345 -
Penicillium nalgiovense Laxa isolated from Antarctica is a new source of the antifungal metabolite amphotericin B.
(2015). Fungal biology and biothechnology, vol. 2 DOI -
Micropropagation of Viola uliginosa (Violaceae) for endangered species conservation and for somaclonal variation-enhanced cyclotide biosynthesis.
(2015). Plant Cell Tissue and Organ Culture, vol. 120, ss. 179-190 DOI -
Backbone-Cyclized Peptide Dimers Derived from Human Cathelicidin Peptide LL-37 Mediate Potent Antimicrobial Activity.
(2014). Journal of Peptide Science, vol. 20, ss. S270-S271 -
Structure and Activity Relationship of the Echinochloa Crus-Galli Antimicrobial Peptide 1.
(2014). Journal of Peptide Science, vol. 20, ss. S278-S279 -
Characterization of Resitant Mutants Points Towards Mechanism of Action of Cyclotides.
(2014). Journal of Peptide Science, vol. 20, ss. S108-S109 -
Antigenotoxic and antioxidant effects of the Mongolian medicinal plant Leptopyrum fumarioides (L): An in vitro study.
(2014). Journal of Ethnopharmacology, vol. 155, ss. 599-606 DOI -
A Systematic Approach to Document Cyclotide Distribution in Plant Species from Genomic, Transcriptomic, and Peptidomic Analysis.
(2013). Biopolymers, vol. 100, ss. 433-437 DOI -
Cycloviolacin O2 (CyO2) Suppresses Productive Infection and Augments the Antiviral Efficacy of Nelfinavir in HIV-1 Infected Monocytic Cells.
(2013). Biopolymers, vol. 100, ss. 471-479 DOI -
Induction of Gliotoxin Secretion in Aspergillus fumigatus by Bacteria-Associated Molecules.
(2014). PLOS ONE, vol. 9, ss. e93685- DOI -
Cyclotide Structure-Activity Relationships: Qualitative and Quantitative Approaches Linking Cytotoxic and Anthelmintic Activity to the Clustering of Physicochemical Forces.
(2014). PLOS ONE, vol. 9, ss. e91430- DOI -
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design.
(2013). Proceedings of the National Academy of Sciences of the United States of America, vol. 110, ss. 21183-21188 DOI -
Bioassay-guided Supercritical Fluid Extraction of Cyclooxygenase-2 Inhibiting Substances in Plantago major L..
(2013). Phytochemical Analysis, vol. 24, ss. 176-183 DOI -
An in vitro Study on the DNA Damaging Effects of Phytochemicals Partially Isolated from an Extract of Glinus lotoides.
(2013). Phytotherapy Research, vol. 27, ss. 507-514 DOI -
Making Ends Meet: Microwave-Accelerated Synthesis of Cyclic and Disulfide Rich Proteins Via In Situ Thioesterification and Native Chemical Ligation.
(2013). International Journal of Peptide Research and Therapeutics, vol. 19, ss. 43-54 DOI -
The traditional medical uses and cytotoxic activities of sixty-one Egyptian plants: Discovery of an active cardiac glycoside from Urginea maritima.
(2013). Journal of Ethnopharmacology, vol. 145, ss. 746-757 DOI -
Optimization of cyclotide extraction parameters.
(2012). Phytochemistry Letters, vol. 5, ss. 776-781 DOI -
Antimicrobial activity of filamentous fungi isolated from highly antibiotic-contaminated river sediment.
(2012). Infection ecology & epidemiology, vol. 2, ss. 11591- DOI -
Chemical Composition and Repellency of Essential Oils From Four Medicinal Plants Against Ixodes ricinus Nymphs (Acari Ixodidae).
(2012). Journal of medical entomology, vol. 49, ss. 1067-1075 DOI -
Fmoc-SPPS based synthesis of bioactive cyclic peptides via N-acylurea intermediates.
(2012). Journal of Peptide Science, vol. 18, ss. S182-S182 DOI -
Strategies and methods for a sustainable search for bioactive compounds.
(2012). Planta Medica, vol. 78, ss. 1031-1032 DOI -
The search for new antibiotic substances from filamentous fungi.
(2012). Planta Medica, vol. 78, ss. 1162-1162 DOI -
Genotoxicity and Cellular Uptake of Cyclotides: Evidence for Multiple Mode of Action.
(2012). Mutation research. Genetic toxicology and environmental mutagenesis, vol. 747, ss. 176-181 DOI -
Anti-schistosomiasis triterpene glycoside from the Egyptian medicinal plant Asparagus stipularis.
(2012). Revista Brasileira de Farmacognosia, vol. 22, ss. 314-318 DOI -
A liquid chromatography-electrospray ionization-mass spectrometry method for quantification of cyclotides in plants avoiding sorption during sample preparation.
(2011). Journal of Chromatography A, vol. 1218, ss. 7964-7970 DOI -
Cyclotides from an Extreme Habitat: Characterization of Cyclic Peptides from Viola abyssinica of the Ethiopian Highlands.
(2011). Journal of natural products (Print), . vol. 74, ss. 727-731 DOI -
Cyclotide-membrane interactions: defining factors of membrane binding, depletion and disruption.
(2011). Biochimica et Biophysica Acta - Biomembranes, vol. 1808, ss. 2665-2673 DOI -
Biomedicine in the environment: Cyclotides constitute potent natural toxins in plants and soil bacteria.
(2011). Environmental Toxicology and Chemistry, vol. 30, ss. 1190-1196 DOI -
Two Brominated Cyclic Dipeptides Released by the Coldwater Marine Sponge Geodia barretti Act in Synergy As Chemical Defense.
(2011). Journal of natural products (Print), vol. 74, ss. 449-454 DOI -
Cyclotides: circular plant peptides for protein engineering.
(2008). Planta Medica, vol. 74, ss. 904-905 -
Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2..
(2008). Planta Medica, vol. 74, ss. 1158-1158 -
Plant cyclotides from an extreme habitat: Characterization of six cyclic peptides from a Violet growing at 3400 m..
(2010). Journal of Peptide Research, vol. 16, ss. 110-110 DOI -
Microwave-assisted total synthesis of macrocyclic cystine knot miniproteins.
(2010). Journal of Peptide Science, vol. 16, ss. 79-79 DOI -
Interlocking disulfides in circular proteins: toward efficient oxidative folding of cyclotides..
(2011). Antioxidants and Redox Signaling, vol. 14, ss. 77-86 DOI -
Anticancer and Chemosensitizing Abilities of Cycloviolacin O2 from Viola odorata and Psyle Cyclotides from Psychotria leptothyrsa.
(2010). Biopolymers, vol. 94, ss. 617-625 DOI -
Natural products in modern life science.
(2010). Phytochemistry Reviews, vol. 9, ss. 279-301 DOI -
Isolation, Characterization, and Bioactivity of Cyclotides from the Micronesian Plant Psychotria leptothyrsa.
(2010). Journal of natural products (Print), vol. 73, ss. 1207-1213 DOI -
An Efficient Approach for the Total Synthesis of Cyclotides by Microwave Assisted Fmoc-SPPS.
(2010). International Journal of Peptide Research and Therapeutics, vol. 16, ss. 167-176 DOI -
Evaluation of toxicity and anti-tumour activity of cycloviolacin O2 in mice..
(2010). Biopolymers, vol. 94, ss. 626-634 DOI -
Cytotoxic potency of small macrocyclic knot proteins: Structure-activity and mechanistic studies of native and chemically modified cyclotides.
(2011). Organic and biomolecular chemistry, vol. 9, ss. 4306-4314 DOI -
The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria.
(2010). Journal of Antimicrobial Chemotherapy, vol. 65, ss. 1964-1971 DOI -
Cyclotide proteins and precursors from the genus Gloeospermum: filling a blank spot in the cyclotide map of Violaceae.
(2010). Phytochemistry, vol. 71, ss. 13-20 DOI -
The Conserved Glu in the Cyclotide Cycloviolacin O2 Has a Key Structural Role.
(2009). ChemBioChem (Print), vol. 10, ss. 2354-2360 DOI -
Mechanism of action of cytotoxic cyclotides: cycloviolacin O2 disrupts lipid membranes.
(2007). Journal of natural products (Print), vol. 70, ss. 643-647 DOI -
Modern pharmacognosy: Connecting biology and chemistry.
(2007). Pure and Applied Chemistry, vol. 79, ss. 763-774 DOI -
A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae).
(2005). The Plant Cell, vol. 17, ss. 3176-3189 DOI
Last modified: 2022-12-16