Analytical Pharmaceutical Chemistry
Drugs in the environment • Drug metabolism and doping control • Metabolomics
Current in the lab
Our recent publications
-
Carlsson, Henrik; Sreenivasan, Akshai P.; Erngren, Ida; Larsson, Anders; Kultima, Kim
Combining the targeted and untargeted screening of environmental contaminants reveals associations between PFAS exposure and vitamin D metabolism in human plasma.
2023
-
Bivehed, Erik; Hellman, Björn; Fan, Yuting; Haglöf, Jakob; Buratovic, Sonja
DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay
2023
-
Nilsson Broberg, Malin; Knych, Heather; Bondesson, Ulf; Pettersson, Curt; Tidstedt, Borje; Stanley, Scott; Thevis, Mario; Hedeland, Mikael
Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control
2023
We congratulate
Mikael Hedeland
Receiving a SEK 3.75 million grant from SRC
Drugs in the environment
Identifying and analysing pharmaceutical substances
Drug metabolism and doping control
Studying metabolites linked to doping control
Metabolomics
Parallel studies of all small molecules in a biological sample
At the heart of the life sciences
Chemical analysis is a central part of many disciplines within life science. For example, high-quality chemical analysis data are often a prerequisite to calculate pharmacokinetic parameters, as a basis for clinical diagnoses, toxicological assessments and forensic conclusions. During pharmaceutical development, chemical analysis is required to determine, among many things, chemical structure, purity and stability.
In Analytical Pharmaceutical Chemistry, we study chemical analysis principles aiming to increase the understanding of relevant physico-chemical mechanisms. The knowledge is utilised in the development of more sensitive and selective analysis methods for complex sample materials. The methods are thence used in interdisciplinary collaborative projects where chemical analysis is central to the acquisition of knowledge.
