Publication list

List of publications in date order

  • Tolmachev, Vladimir; Orlova, Anna

    Affibody Molecules as Targeting Vectors for PET Imaging

    Part of Cancers, 2020.

    Open access
  • Rinne, Sara S.; Leitao, Charles Dahlsson; Saleh-nihad, Zahra; Mitran, Bogdan et al.

    Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules

    Part of International Journal of Molecular Sciences, 2020.

    Open access
  • Deyev, Sergey M.; Vorobyeva, Anzhelika; Schulga, Alexey; Abouzayed, Ayman et al.

    Effect of a radiolabel biochemical nature on tumor-targeting properties of EpCAM-binding engineered scaffold protein DARPin Ec1

    Part of International Journal of Biological Macromolecules, p. 216-225, 2020.

    Open access
  • Vorobyeva, Anzhelika; Konovalova, Elena; Xu, Tianqi; Schulga, Alexey et al.

    Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1

    Part of International Journal of Molecular Sciences, 2020.

    Open access
  • Ding, Haozhong; Altai, Mohamed; Yin, Wen; Lindbo, Sarah et al.

    HER2-Specific Pseudomonas Exotoxin A PE25 Based Fusions: Influence of Targeting Domain on Target Binding, Toxicity, and In Vivo Biodistribution

    Part of Pharmaceutics, 2020.

    Open access
  • Mitran, Bogdan; Andersson, Ken Gosta; Lindström, Elin; Garousi, Javad et al.

    Affibody-mediated imaging of EGFR expression in prostate cancer using radiocobalt-labeled DOTA-Z(EGFR:2377)

    Part of Oncology Reports, p. 534-542, 2019.

  • Mitran, Bogdan; Varasteh, Zohreh; Abouzayed, Ayman; Rinne, Sara S. et al.

    Bispecific GRPR-antagonistic anti-PSMA/GRPR heterodimer for PET and SPECT diagnostic imaging of prostate cancer

    Part of Cancers, 2019.

    Open access
  • Garousi, Javad; Huizing, Fokko J.; Vorobyeva, Anzhelika; Mitran, Bogdan et al.

    Comparative evaluation of affibody- and antibody fragments-based CAIX imaging probes in mice bearing renal cell carcinoma xenografts

    Part of Scientific Reports, 2019.

    Open access
  • Garousi, Javad; Lindbo, Sarah; Borin, Jesper; von Witting, Emma et al.

    Comparative evaluation of dimeric and monomeric forms of ADAPT scaffold protein for targeting of HER2-expressing tumours

    Part of European journal of pharmaceutics and biopharmaceutics, p. 37-48, 2019.

    Open access
  • Deyev, Sergey; Vorobyeva, Anzhelika; Schulga, Alexey; Proshkina, Galina et al.

    Comparative Evaluation of Two DARPin Variants: Effect of Affinity, Size, and Label on Tumor Targeting Properties

    Part of Molecular Pharmaceutics, p. 995-1008, 2019.

  • Vorobyeva, Anzhelika; Schulga, Alexey; Konovalova, Elena; Güler, Rezan et al.

    Comparison of tumor-targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2

    Part of International Journal of Oncology, p. 1209-1220, 2019.

    Open access
  • Oroujeni, Maryam; Abouzayed, Ayman; Lundmark, Fanny; Mitran, Bogdan et al.

    Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Counterpart

    Part of Pharmaceutics, 2019.

    Open access
  • Rosestedt, Maria; Andersson, Ken G.; Rinne, Sara S.; Leitao, Charles Dahlsson et al.

    Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake

    Part of Scientific Reports, 2019.

    Open access
  • Ding, Haozhong; Altai, Mohamed; Rinne, Sara S.; Vorobyeva, Anzhelika et al.

    Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody-DM1 Drug Conjugates

    Part of Cancers, 2019.

    Open access
  • Rinne, Sara S.; Leitao, Charles Dahlsson; Gentry, Joshua; Mitran, Bogdan et al.

    Increase in negative charge of 68Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody molecules

    Part of Scientific Reports, 2019.

    Open access
  • Vorobyeva, Anzhelika; Schulga, Alexey; Rinne, Sara S.; Günther, Tyran et al.

    Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging

    Part of International Journal of Molecular Sciences, 2019.

    Open access
  • Dahlsson Leitao, Charles; Rinne, Sara S.; Mitran, Bogdan; Vorobyeva, Anzhelika et al.

    Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of 68Ga-Labeled Tracers

    Part of International Journal of Molecular Sciences, 2019.

    Open access
  • Vorobyeva, Anzhelika; Schulga, Alexey; Konovalova, Elena; Guler, Rezan et al.

    Optimal composition and position of histidine-containing tags improves biodistribution of Tc-99m-labeled DARP in G3

    Part of Scientific Reports, 2019.

    Open access
  • Rinne, Sara S.; Leitao, Charles Dahlsson; Mitran, Bogdan; Bass, Tarek Z. et al.

    Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111

    Part of Scientific Reports, 2019.

    Open access
  • Liu, Hao; Lindbo, Sarah; Ding, Haozhong; Altai, Mohamed et al.

    Potent and specific fusion toxins consisting of a HER2-binding, ABD-derived affinity protein, fused to truncated versions of Pseudomonas exotoxin A

    Part of International Journal of Oncology, p. 309-319, 2019.

  • Mitran, Bogdan; Thisgaard, Helge; Rinne, Sara S.; Dam, Johan Hygum et al.

    Selection of an optimal macrocyclic chelator improves the imaging of prostate cancer using cobalt-labeled GRPR antagonist RM26

    Part of Scientific Reports, 2019.

    Open access
  • von Witting, Emma; Garousi, Javad; Lindbo, Sarah; Vorobyeva, Anzhelika et al.

    Selection of the optimal macrocyclic chelators for labeling with 111In and 68Ga improves contrast of HER2 imaging using engineered scaffold protein ADAPT6

    Part of European journal of pharmaceutics and biopharmaceutics, p. 109-120, 2019.

    Open access
  • Westerlund, Kristina; Vorobyeva, Anzhelika; Mitran, Bogdan; Orlova, Anna et al.

    Site-specific conjugation of recognition tags to trastuzumab for peptide nucleic acid-mediated radionuclide HER2 pretargeting

    Part of Biomaterials, p. 73-85, 2019.

    Open access
  • Abouzayed, Ayman; Yim, Cheng-Bin; Mitran, Bogdan; Rinne, Sara S. et al.

    Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

    Part of Pharmaceutics, 2019.

    Open access
  • Mitran, Bogdan; Rinne, Sara S.; Konijnenberg, Mark W.; Maina, Theodosia et al.

    Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177Lu-DOTAGA-PEG2-RM26

    Part of International Journal of Cancer, p. 3347-3358, 2019.

    Open access
  • Altai, Mohamed; Liu, Hao; Ding, Haozhong; Mitran, Bogdan et al.

    Affibody-derived drug conjugates: Potent cytotoxic molecules for treatment of HER2 over-expressing tumors

    Part of Journal of Controlled Release, p. 84-95, 2018.

  • Oroujeni, Maryam; Garousi, Javad; Andersson, K.; Löfblom, J. et al.

    Comparative evaluation of anti-EFGR affibody molecules labelled with gallium-68 and zirconium-89 using desferrioxamine B as a chelator

    Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S674-S675, 2018.

  • Vorobyeva, Anzhelika; Bragina, Olga; Altai, Mohamed; Mitran, Bogdan et al.

    Comparative Evaluation of Radioiodine and Technetium-Labeled DARPin 9_29 for Radionuclide Molecular Imaging of HER2 Expression in Malignant Tumors

    Part of Contrast Media & Molecular Imaging, 2018.

    Open access
  • Summer, Dominik; Garousi, Javad; Oroujeni, Maryam; Mitran, Bogdan et al.

    Cyclic versus Noncyclic Chelating Scaffold for Zr-89-Labeled ZEGFR:2377 Affibody Bioconjugates Targeting Epidermal Growth Factor Receptor Overexpression

    Part of Molecular Pharmaceutics, p. 175-185, 2018.

    Open access
  • Vorobyeva, Anzhelika; Westerlund, K.; Mitran, Bogdan; Altai, Mohamed et al.

    Development of a PET Imaging Approach for Selection of Patients for Affibody-Based PNA-Mediated Pretargeted Radionuclide Therapy

    Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S104-S104, 2018.

  • Vorobyeva, Anzhelika; Westerlund, Kristina; Mitran, Bogdan; Altai, Mohamed et al.

    Development of an optimal imaging strategy for selection of patients for affibody-based PNA-mediated radionuclide therapy

    Part of Scientific Reports, 2018.

    Open access
  • Honarvar, Hadis; Calce, Enrica; Doti, Nunzianna; Langella, Emma et al.

    Evaluation of HER2-specific peptide ligand for its employment as radiolabeled imaging probe

    Part of Scientific Reports, 2018.

    Open access
  • Vorobyeva, Anzhelika; Bragina, O.; Altai, Mohamed; Mitran, Bogdan et al.

    Evaluation of Radioiodine and Technetium-Labeled DARPin 9_29 for Molecular Imaging of HER2 Expression in Cancer Using SPECT

    Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S678-S679, 2018.

  • Orlova, Anna; Bass, Tarek Z.; Rinne, Sara S.; Leitao, Charles Dahlsson et al.

    Evaluation of the Therapeutic Potential of a HER3-Binding Affibody Construct TAM-HER3 in Comparison with a Monoclonal Antibody, Seribantumab

    Part of Molecular Pharmaceutics, p. 3394-3403, 2018.

  • Mitran, Bogdan; Rinne, Sara S.; Azamy, F.; Vorobyeva, Anzhelika et al.

    GRPR-targeted radiotherapy using the Lu-177-labeled GRPR-antagonist DOTAGA-PEG(2)-RM26

    Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S29-S30, 2018.

  • Orlova, Anna; Rosestedt, Maria; Rinne, Sara S.; Mitran, Bogdan et al.

    Imaging contrast of HER3 expression using monomeric affibody-based imaging probe can be improved by co-injection of affibody trimer

    Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S673-S673, 2018.

  • Oroujeni, Maryam; Andersson, Ken G.; Steinhardt, Xenia; Altai, Mohamed et al.

    Influence of composition of cysteine-containing peptide-based chelators on biodistribution of 99mTc-labeled anti-EGFR affibody molecules

    Part of Amino Acids, p. 981-994, 2018.

    Open access
  • Altai, Mohamed; Leitao, Charles Dahlsson; Rinne, Sara S.; Vorobyeva, Anzhelika et al.

    Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs

    Part of CELLS, 2018.

    Open access
  • Tolmachev, Vladimir; Grönroos, Tove J; Yim, Cheng-Bin; Garousi, Javad et al.

    Molecular design of radiocopper-labelled Affibody molecules

    Part of Scientific Reports, 2018.

    Open access
  • Rinne, Sara S.; Mitran, Bogdan; Vorobyeva, Anzhelika; Leitao, C. Dahlsson et al.

    Optimization of molecular design of Ga-68-labeled affibody molecule for PET imaging of HER3 expression

    Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S109-S109, 2018.

  • Lindbo, Sarah; Garousi, Javad; Mitran, Bogdan; Vorobyeva, Anzhelika et al.

    Optimized Molecular Design of ADAPT-Based HER2-Imaging Probes Labeled with 111In and 68Ga

    Part of Molecular Pharmaceutics, p. 2674-2683, 2018.

  • Summer, D; Garousi, Javad; Oroujeni, Maryam; Mitran, Bogdan et al.

    PP15 89Zr-Siderophore-Affibody conjugates for imaging EGFR expression

    Part of EJNMMI Research, 2018.

  • Oroujeni, Maryam; Garousi, Javad; Andersson, Ken G.; Lofblom, John et al.

    Preclinical Evaluation of [Ga-68]Ga-DFO-ZEGFR:2377: A Promising Affibody-Based Probe for Noninvasive PET Imaging of EGFR Expression in Tumors

    Part of CELLS, 2018.

    Open access
  • Mitran, Bogdan; Güler, Rezan; Roche, Francis P.; Lindström, Elin et al.

    Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

    Part of Theranostics, p. 4462-4476, 2018.

    Open access
  • Westerlund, Kristina; Altai, Mohamed; Mitran, Bogdan; Konijnenberg, Mark et al.

    Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle

    Part of Journal of Nuclear Medicine, p. 1092-1098, 2018.

  • Lindbo, Sarah; Garousi, Javad; Mitran, Bogdan; Buijs, Jos et al.

    Radionuclide tumor targeting using ADAPT scaffold proteins: aspects of label positioning and residualizing properties of the label

    Part of Journal of Nuclear Medicine, p. 93-99, 2018.

  • Krasniqi, Ahmet; D'Huyvetter, Matthias; Devoogdt, Nick; Frejd, Fredrik Y. et al.

    Same-day imaging using small proteins: Clinical experience and translational prospects in oncology.

    Part of Journal of Nuclear Medicine, p. 885-891, 2018.

  • Mitran, Bogdan; Thisgaard, H.; Rinne, Sara S.; Rosenström, Ulrika et al.

    Selection of optimal macrocyclic chelator for high contrast PET imaging of gastrin releasing peptide receptor using cobalt-labeled bombesin antagonist RM26

    Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S672-S673, 2018.

  • Garousi, Javad; Lindbo, S.; Mitran, Bogdan; Vorobyeva, Anzhelika et al.

    Selection of the most optimal ADAPT6-based probe for imaging of HER2 using PET and SPECT

    Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S77-S78, 2018.

  • Tolmachev, Vladimir; Yim, Cheng-Bin; Rajander, Johan; Perols, Anna et al.

    Comparative Evaluation of Anti-HER2 Affibody Molecules Labeled with Cu-64 Using NOTA and NODAGA

    Part of Contrast Media & Molecular Imaging, p. 1-12, 2017.

    Open access