Publikationer

Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2)

Lu, Lu; Åkerbladh, Linda; Ahmad, Shabbir; Konda, Vivek et al.

Ingår i ACS Infectious Diseases, s. 482-498, 2022.

DOI för Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2) Ladda ner fulltext (pdf) av Synthesis and in vitro biological evaluation of quinolinyl pyrimidines targeting type II NADH-dehydrogenase (NDH-2)

2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands

Roy, Tamal; Petersen, Nadia N.; Gopalan, Greeshma; Gising, Johan et al.

Ingår i Bioorganic & Medicinal Chemistry, 2022.

DOI för 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands Ladda ner fulltext (pdf) av 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands

Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands

Lundmark, Fanny; Olanders, Gustav; Rinne, Sara Sophie; Abouzayed, Ayman et al.

Ingår i Pharmaceutics, 2022.

DOI för Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands Ladda ner fulltext (pdf) av Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands

Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures

Stam, Frida; Lind, Sara Florén; Schroff, Anja; Zelleroth, Sofia et al.

Ingår i Current Issues in Molecular Biology, s. 5000-5012, 2022.

DOI för Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures Ladda ner fulltext (pdf) av Hydrogen Peroxide Induced Toxicity Is Reversed by the Macrocyclic IRAP-Inhibitor HA08 in Primary Hippocampal Cell Cultures

Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds

Gopalan, Greeshma; Palo-Nieto, Carlos; Petersen, Nadia N.; Hallberg, Mathias et al.

Ingår i Bioorganic & Medicinal Chemistry, 2022.

DOI för Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds Ladda ner fulltext (pdf) av Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds

P-119 - Efficient cartridge-based synthesis of a novel [18F]tetrazine for large molecule labelling

Rokka, Johanna; Syvaenen, Stina; Odell, Luke R.; Schlein, Eva et al.

Ingår i Nuclear Medicine and Biology, 2022.

Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems

Fridjonsdottir, Elva; Vallianatou, Theodosia; Mantas, Ioannis; Shariatgorji, Reza et al.

Ingår i ACS Chemical Biology, s. 147-158, 2022.

DOI för Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems Ladda ner fulltext (pdf) av Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems

¹⁸F-Radiolabeling and Preliminary Evaluation of a HSP₉₀ ligand

Nordeman, Patrik; Jayendra, Z. P.; Briard, E.; Li, Su-Chen et al.

Ingår i European Journal of Pharmaceutical Sciences, 2021.

DOI för ¹⁸F-Radiolabeling and Preliminary Evaluation of a HSP₉₀ ligand

Mass spectrometry imaging identifies abnormally elevated brain L-DOPA levels and extrastriatal monoaminergic dysregulation in L-DOPA-induced dyskinesia

Fridjonsdottir, Elva; Shariatgorji, Mohammadreza; Nilsson, Anna; Vallianatou, Theodosia et al.

Ingår i Science Advances, 2021.

DOI för Mass spectrometry imaging identifies abnormally elevated brain L-DOPA levels and extrastriatal monoaminergic dysregulation in L-DOPA-induced dyskinesia Ladda ner fulltext (pdf) av Mass spectrometry imaging identifies abnormally elevated brain L-DOPA levels and extrastriatal monoaminergic dysregulation in L-DOPA-induced dyskinesia

Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Rosestedt, Maria; Velikyan, Irina; Rosenström, Ulrika; Estrada, Sergio et al.

Ingår i Nuclear Medicine and Biology, s. 54-62, 2021.

DOI för Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1 Ladda ner fulltext (pdf) av Radiolabelling and positron emission tomography imaging of a high-affinity peptide binder to collagen type 1

Spatial visualization of comprehensive brain neurotransmitter systems and neuroactive substances by selective in situ chemical derivatization mass spectrometry imaging

Shariatgorji, Reza; Nilsson, Anna; Fridjonsdottir, Elva; Strittmatter, Nicole et al.

Ingår i Nature Protocols, s. 3298-3321, 2021.

DOI för Spatial visualization of comprehensive brain neurotransmitter systems and neuroactive substances by selective in situ chemical derivatization mass spectrometry imaging

The Wittig Bioconjugation of Maleimide Derived, Water Soluble Phosphonium Ylides to Aldehyde-Tagged Proteins

Hartmann, Rafael W.; Pijnappel, Matthijs; Nilvebrant, Johan; Helgudottir, Hildur Run et al.

Ingår i Organic and biomolecular chemistry, s. 10417-10423, 2021.

DOI för The Wittig Bioconjugation of Maleimide Derived, Water Soluble Phosphonium Ylides to Aldehyde-Tagged Proteins Ladda ner fulltext (pdf) av The Wittig Bioconjugation of Maleimide Derived, Water Soluble Phosphonium Ylides to Aldehyde-Tagged Proteins

N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

Wannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica et al.

Ingår i Bioorganic & Medicinal Chemistry, 2021.

DOI för N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

Sustainability in drug discovery

Wynendaele, Evelien; Furman, Christophe; Wielgomas, Bartosz; Larsson, Per et al.

Ingår i Medicine in Drug Discovery, 2021.

DOI för Sustainability in drug discovery Ladda ner fulltext (pdf) av Sustainability in drug discovery

Improved Radiolytic Stability of a ⁶⁸Ga-labelled Collagelin Analogue for the Imaging of Fibrosis

Velikyan, Irina; Rosenström, Ulrika; Rosestedt, Maria; Eriksson, Olof et al.

Ingår i Pharmaceuticals, 2021.

DOI för Improved Radiolytic Stability of a ⁶⁸Ga-labelled Collagelin Analogue for the Imaging of Fibrosis Ladda ner fulltext (pdf) av Improved Radiolytic Stability of a ⁶⁸Ga-labelled Collagelin Analogue for the Imaging of Fibrosis

Synthesis of substituted 3,4-dihydroquinazolinones via a metal free Leuckart-Wallach type reaction

Bokale-Shivale, Suvarna; Amin, Mohammad A.; Sawant, Rajiv T.; Stevens, Marc Y. et al.

Ingår i RSC Advances, s. 349-353, 2021.

DOI för Synthesis of substituted 3,4-dihydroquinazolinones via a metal free Leuckart-Wallach type reaction Ladda ner fulltext (pdf) av Synthesis of substituted 3,4-dihydroquinazolinones via a metal free Leuckart-Wallach type reaction

PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Cheung, Pierre; Zhang, Bo; Puuvuori, Emmi; Estrada, Sergio et al.

Ingår i Biomedicines, 2021.

DOI för PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs Ladda ner fulltext (pdf) av PET Imaging of GPR44 by Antagonist [C-11]MK-7246 in Pigs

Pyrimidyn‐Based Dynamin Inhibitors as Novel Cytotoxic Agents

Odell, Luke R.; Chau, Ngoc; Russell, Cecilia C.; Young, Kelly A. et al.

Ingår i ChemMedChem, 2021.

DOI för Pyrimidyn‐Based Dynamin Inhibitors as Novel Cytotoxic Agents

Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

Isaksson, Rebecka; Casselbrant, Anna; Elebring, Erik; Hallberg, Mathias et al.

Ingår i European Journal of Pharmacology, 2020.

DOI för Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages Ladda ner fulltext (pdf) av Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

Engen, Karin; Reddy Vanga, Sudarsana; Lundbäck, Thomas; Agalo, Faith et al.

Ingår i ChemistryOpen, s. 325-337, 2020.

DOI för Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors Ladda ner fulltext (pdf) av Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

Barlow, Nicholas; Reddy Vanga, Sudarsana; Sävmarker, Jonas; Sandström, Anja et al.

Ingår i RSC Medicinal chemistry, s. 234-244, 2020.

DOI för Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor

Mpakali, Anastasia; Saridakis, Emmanuel; Giastas, Petros; Maben, Zachary et al.

Ingår i ACS Medicinal Chemistry Letters, s. 1429-1434, 2020.

DOI för Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor

Regio- and Stereoselective Synthesis of Allylic Spiroethers (Spirobenzofuranes) via an Intramolecular Mizoroki-Heck Reaction

Adeyemi, Ahmed; Odell, Luke R.; Larhed, Mats

Ingår i Journal of Organic Chemistry, s. 7648-7657, 2020.

DOI för Regio- and Stereoselective Synthesis of Allylic Spiroethers (Spirobenzofuranes) via an Intramolecular Mizoroki-Heck Reaction

Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

Lundmark, Fanny; Abouzayed, Ayman; Mitran, Bogdan; Rinne, Sara S. et al.

Ingår i Pharmaceutics, 2020.

DOI för Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model Ladda ner fulltext (pdf) av Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

Turning Information Dissipation into Dissemination: Instagram as a Communication Enhancing Tool during the COVID-19 Pandemic and Beyond

Ye, Sofie; Hartmann, Rafael; Söderström, Marcus; Amin, Mohammad A. et al.

Ingår i Journal of Chemical Education, s. 3217-3222, 2020.

DOI för Turning Information Dissipation into Dissemination: Instagram as a Communication Enhancing Tool during the COVID-19 Pandemic and Beyond

From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase

Hallberg, Mathias; Larhed, Mats

Ingår i Frontiers in Pharmacology, 2020.

DOI för From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase Ladda ner fulltext (pdf) av From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase

Rational Design of Azastatin as a Potential ADC Payload with Reduced Bystander Killing.

Hartmann, Rafael; Fahrner, Raphael; Shevshenko, Denys; Fryknäs, Mårten et al.

Ingår i ChemMedChem, s. 2500-2512, 2020.

DOI för Rational Design of Azastatin as a Potential ADC Payload with Reduced Bystander Killing. Ladda ner fulltext (pdf) av Rational Design of Azastatin as a Potential ADC Payload with Reduced Bystander Killing.

A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Isaksson, Rebecka; Lindman, Jens; Wannberg, Johan; Sallander, Jessica et al.

Ingår i ChemistryOpen, s. 114-125, 2019.

DOI för A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode Ladda ner fulltext (pdf) av A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Palladium(0)-Catalyzed Carbonylative Synthesis of N-Acylsulfonamides via Regioselective Acylation

Schembri, Luke S; Eriksson, Jonas; Odell, Luke R.

Ingår i Journal of Organic Chemistry, s. 6970-6981, 2019.

DOI för Palladium(0)-Catalyzed Carbonylative Synthesis of N-Acylsulfonamides via Regioselective Acylation

Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

Abouzayed, Ayman; Yim, Cheng-Bin; Mitran, Bogdan; Rinne, Sara S. et al.

Ingår i Pharmaceutics, 2019.

DOI för Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer Ladda ner fulltext (pdf) av Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer