Uppsala University • 14–15 September 2022

PKPD Reserch in Uppsala

PKPD at Uppsala University

We focus on fundamental and functional aspects of pharmacokinetics-pharmacodynamics in health and disease. Within translational PKPD we address conversion of pharmacokinetic data from the preclinical to the clinical setting. This is needed for optimizing drug discovery processes and promoting efficient treatment of CNS diseases.

We are interested in brain drug delivery in relation to transport processes of small and large molecules across the blood-brain barrier. Using concepts and methodologies developed in the group, we explore brain regional drug disposition, including the influence of diseases, with focus on the pharmacologically relevant unbound concentrations. We also emphasize bridging expertise within academia and pharmaceutical industry to seek excellence in method development for better therapeutics treating CNS disorders.

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Last modified: 2022-09-08